The scientists tethered together two llama antibodies against influenza A and two against influenza B to create a “multidomain” antibody. With their Scripps Research colleagues, Ian Wilson and Professor Andrew Ward, PhD, led the x-ray and electron microscopy structural studies to show exactly where this multidomain antibody was binding to influenza proteins. They found that the antibody could target several vulnerable sites on influenza A and B. This means the antibody was cross-reactive and may have the ability to protect against all circulating strains of the virus that affect humans, as well as new subtypes that could mutate to cause pandemics.See it on Scoop.it, via Viruses, Immunology & Bioinformatics from Virology.uvic.ca
Tethered antibodies present a potential new approach to prevent influenza virus infections
Source: Viral Bioinformatics

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